EAHAD DBs Latest: Mar 2022 - F7 Database Updated to End 2021

See Citing Us (below) for links to our recent EAHAD-DB publications.

F5 Variants and DB Features: Protein Structure Now Added

Variants in the gene (F5) that codes for coagulation factor V (FV) may be associated both with rare FV deficiency and bleeding, but also with more common prothrombotic (hypercoagulable) states.

There are currently 209 unique variants in the F5 gene compiled within this database corresponding to 443 individual cases from c.280 different families. Approximately half the cases are single reports, the remainder taken from 64 families with multiple described cases.

In order to help interpret their significance in real-life cases, we provide amino-acid alignments (to assist in estimating the effects of missense variants), together with information on common variants of F5. Read the Help Page for a more detailed feature description.

Simple FV Amino Acid Search

HGVS
Legacy

F5 Exon and Intron based search

Exon
Intron

Reference Sequences and Nomenclature (HGVS and Legacy)  


Protein Structure Representations  


F5 Variants - Haemorrhagic or Thrombotic?  


Acknowledgements


Citing Us


Latest Release- Version 2.0 (April 2022)  


Links to the other EAHAD-DB Databases  


Have you or someone you know been diagnosed with Factor V deficiency?  

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